Protein Metabolism

Urea is the principal disposal form of amino groups of amino acids, and about 90% of nitrogen containing compounds of urine. At first, the amino groups of amino acids are converted into glutamate by the process of transamination reaction.Then, glutamate can enter into oxidative deamination reaction, and provide ammonia. Finally, most of the toxic ammonia is converted to urea by ...

Transamination is the conversion of one amino acid to corresponding keto acid with simultaneous conversion of another keto acid to an amino acid. In short, it is the interconversion between a pair of amino acid and a pair of ketoacid. All amino acids except lysine, proline, hydroxyproline, and, threonine participate in transamination. Reaction of transamination is reversible and catalyzed by ...

Amino acids are the monomer of protein containing both amino group and carboxyl group. Structure of amino acids: Each amino acid has an α-amino group (- NH3+), an α-carboxyl group (- COOH), and a distinctive side chain (R- group) attached to the α-carbon atom. Types of amino acids: 20 amino acids are necessary for human body. Of these, some can ...

Dietary proteins are digested in the intestine and produced their constituent amino acids that are absorbed into the blood stream. Amino acids are also obtained in the blood stream from normal body protein degradation or from de novo synthesis. Amino acids are safely locked by the α-amino group. Removal of α-amino group is essential for generating energy from amino acids, ...